Genetic Testing Registry

The Genetic Testing Registry (GTR®) provides a central location for voluntary submission of genetic test information by providers. The scope includes the test's purpose, methodology, validity, evidence of the test's usefulness, and laboratory contacts and credentials. The overarching goal of the GTR is to advance the public health and research into the genetic basis of health and disease.


The website includes a number of presentations about how to use this valuable genetic testing resource which would be suitable for trainees or those new to the GTR.



Type Website
CME Available No
Topic
Cost Free
Note


Date of Resource

Genomic Competencies

Experts from the disciplines listed below have tagged this resource as fulfulling genomic competencies.

Pharmacist

  • Pharmacogenetics/Pharmacogenomics
    • P1:   To demonstrate an understanding of how genetic variation in a large number of proteins, including drug transporters, drug metabolizing enzymes, direct protein targets of drugs, and other proteins (e.g. signal transduction proteins) influence pharmacokinetics and pharmacodynamics related to pharmacologic effect and drug response
    • P3:   Recognize the availability of evidence based guidelines that synthesize information relevant to genomic/pharmacogenomic tests and selection of drug therapy (e.g. Clinical Pharmacogenomics Implementation Consortium)

Physician Assistant

  • Patient Care
    • 3:   Distinguish between genetic screening and genetic testing
    • 4:   Incorporate genetic tests into patient management

Physician

  • Genomic Testing
    • P-GT2A:   Patient Care
      • 2A1:   Discuss the indications for genomic testing - specifically the benefits, risks, and alternatives
      • 2A2:   Explain the implications of placing genomic test results in the patient’s medical record
      • 2A3:   Discuss the possibility of incidental findings and how they will be handled
      • 2A4:   Discuss risks of having genomic testing done: e.g., psychological implications for the individual as well as the family; the potential for discrimination; and the potential effect on insurance coverage.
      • 2A5:   Explain to the patient issues of costs and financial coverage of genomic testing
      • 2A6:   Order, interpret, and communicate the results of appropriate genomic tests, within the physician’s scope of practice
      • 2A7:   Provide referral to an appropriate specialist for genomic testing of a condition outside the physician’s scope of practice
      • 2A8:   Respond to the results of an abnormal genetic screening test, such as newborn screening, including immediate management and appropriate referral
    • P-GT2B:   Knowledge for Practice
      • 2B1:   Describe the major forms of genomic variability
      • 2B2:   Explain how different genomic changes may result in different phenotypes
      • 2B3:   Recognize that genomic tests require interpretation with respect to the patient’s clinical status (e.g., pathogenic, likely pathogenic, benign)
      • 2B4:   Explain the concepts of analytic validity, clinical validity, clinical utility as they relate to genomic testing
      • 2B5:   Recognize that medically ’non-actionable’ genomic results can be useful to the patient and family (i.e., personal utility)
  • Somatic Genomics
    • P-SG4A:   Patient Care
      • 4A1:   Identify or facilitate identification of patients who may benefit from genomic testing of tissue
      • 4A2:   Explain the benefits and limitations of somatic genomic testing to the patient, including implications regarding treatment of their condition and clarification of his/her prognosis
      • 4A3:   Ensure that tissue biopsy procedures are coordinated to make certain that appropriate and sufficient material is obtained for testing
      • 4A4:   Integrate genomic testing results into the patient-care plan
    • P-SG4B:   Knowledge for Practice
      • 4B1:   Explain the concept of somatic genetic change
      • 4B2:   Describe the role of genomic changes in the pathophysiology and treatment of cancer
      • 4B3:   Explain how genomic testing can be used to guide choice of therapy and adjust drug dosage in patients with cancer

Nurse

  • Professional Responsibilities
    • PR-3:   Examine competency of practice
      • PR3-K1:   Scope of nursing practice in relation to genetics/genomics
        • PR3-1:   Identify relevance of genetics/genomics to practice of your discipline.
        • PR3-2:   Demonstrate awareness of the boundaries of one's own professional practice in relation to genetics/genomics.
        • PR3-3:   Perform regular self assessments to identify knowledge and skills deficits that could impact the quality of nursing care one provides to clients in need of genetic/genomic guidance, referral and resources.
        • PR3-4:   Take action to meet identified knowledge and skills deficits related to genetics and genomics.
      • PR3-K2:   Role of specialist genetic/genomic services
        • PR3-1:   Identify relevance of genetics/genomics to practice of your discipline.
        • PR3-2:   Demonstrate awareness of the boundaries of one's own professional practice in relation to genetics/genomics.
        • PR3-3:   Perform regular self assessments to identify knowledge and skills deficits that could impact the quality of nursing care one provides to clients in need of genetic/genomic guidance, referral and resources.
        • PR3-4:   Take action to meet identified knowledge and skills deficits related to genetics and genomics.
      • PR3-K3:   Interprofessional resources
        • PR3-1:   Identify relevance of genetics/genomics to practice of your discipline.
        • PR3-2:   Demonstrate awareness of the boundaries of one's own professional practice in relation to genetics/genomics.
        • PR3-3:   Perform regular self assessments to identify knowledge and skills deficits that could impact the quality of nursing care one provides to clients in need of genetic/genomic guidance, referral and resources.
        • PR3-4:   Take action to meet identified knowledge and skills deficits related to genetics and genomics.

Genetic Counselor

  • Genetics Expertise and Analysis
    • 4:   Identify, assess, facilitate, and integrate genetic testing options in genetic counseling practice.
      • 4a:   Investigate the availability, analytic validity, clinical validity, and clinical utility of screening, diagnostic and predictive genetic/genomic tests.
      • 4b:   Evaluate and assess laboratories and select the most appropriate laboratory and test based on the clinical situation.