How to Search ClinVar

ClinVar is a  freely accessible, public archive of reports of the relationships among human variations and phenotypes, with supporting evidence. The information in ClinVar is important in helping clinicians assess the evidence supporting or refuting pathogenicity of a genetic variant. The link provided is for tutorials on how to search ClinVar successfully. 


Type Website
CME Available No
Topic
Cost Free
Note


Date of Resource

Genomic Competencies

Experts from the disciplines listed below have tagged this resource as fulfulling genomic competencies.

Pharmacist

  • Basic Genetic Concepts
    • B1:   To demonstrate an understanding of the basic genetic/genomic concepts and nomenclature
    • B3:   To identify drug and disease associated genetic variations that facilitate development of prevention, diagnostic and treatment strategies and appreciate there are differences in testing methodologies and are aware of the need to explore these differences in drug literature evaluation
  • Genetics and Disease
    • G1:   To understand the role of genetic factors in maintaining health and preventing disease
    • G2:   To assess the difference between clinical diagnosis of disease and identification of genetic predisposition to disease (genetic variation is not strictly correlated with disease manifestation)

Physician Assistant

  • Practiced-based Learning and Improvement
    • 1:   Use information technology to obtain current and credible information about genetics for self, patients, and colleagues

Genetic Counselor

  • Genetics Expertise and Analysis
    • 4:   Identify, assess, facilitate, and integrate genetic testing options in genetic counseling practice.
      • 4a:   Investigate the availability, analytic validity, clinical validity, and clinical utility of screening, diagnostic and predictive genetic/genomic tests.
      • 4b:   Evaluate and assess laboratories and select the most appropriate laboratory and test based on the clinical situation.
      • 4c:   Identify and discuss the potential benefits, risks, limitations and costs of genetic testing.
      • 4d:   Coordinate and facilitate the ordering of appropriate genetic testing for the client.
      • 4e:   Interpret the clinical implications of genetic test reports.
      • 4f:   Recognize and differentiate specific considerations relevant to genetic versus genomic and clinical versus research testing in terms of the informed consent process, results disclosure, institutional review board (IRB) guidelines, and clinical decision-making.
  • Professional Development & Practice
    • 20:   Support client and community interests in accessing, or declining, social and health services and clinical research.
      • 20a:   Display initiative for lifelong learning.
      • 20b:   Recognize one's limitations and capabilities in the context of genetic counseling practice.
      • 20c:   Seek feedback and respond appropriately to performance critique.
      • 20d:   Demonstrate a scholarly approach to genetic counseling, including using available evidence-based principles in the preparation and execution of a genetic counseling encounter.
      • 20e:   Identify appropriate individual and/or group opportunities for ongoing personal supervision and mentorship.
      • 20f:   Accept responsible for one's physical and emo- tional health as it impacts on professional performance.
      • 20g:   Recognize and respect professional boundaries between clients, colleagues, and supervisors.