Case study created by the Inter-Society Coordinating Committee (ISCC) Case Studies Working Group (https://www.genome.gov/27560578/iscc-case-studies-working-group-case-studies/iscc-case-studies-working-group-case-studies/) in collaboration with the National Human Genome Research Institute.
Type of Case Study: Genomic-based therapeutics, Pharmacogenomic. Clinicians often best understand the value of new information in context through case-based learning. The genetic and genomic case studies represent examples of scenarios physicians are likely to encounter in practice. These cases are designed to present pertinent information, highlight decision points, provide background content about why certain decisions are appropriate, and link to the evidence base of knowledge and guidelines currently available. They incorporate competencies and entrustable professional activities identified by the ISCC's Competency Working Group.
Note to Physician Assistants: Click on the link titled "Proposed Use Case Template and Example" and scroll down to see the case describing HLA-B alleles and adverse events related to use of carbamazepine.
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Experts from the disciplines listed below have tagged this resource as fulfulling genomic competencies.