Genomics and Precision Health

Precision medicine is a rapidly evolving approach to disease treatment and prevention that matches treatments to patients based on individual genetic variability. To help clinicians understand the latest developments in precision medicine so they can make the most informed decisions for their patients JAMA in 2017 is publishing a series of essays to explain the state of the field, its concepts, and technologies.


Type Website
CME Available Yes
Topic
Cost Free
Note

For Genetic Counselor: Audiocast with articles (JAMA insights) on relevant personalized medicine topics.

Date of Resource

Genomic Competencies

Experts from the disciplines listed below have tagged this resource as fulfulling genomic competencies.

Pharmacist

  • Basic Genetic Concepts
    • B3:   To identify drug and disease associated genetic variations that facilitate development of prevention, diagnostic and treatment strategies and appreciate there are differences in testing methodologies and are aware of the need to explore these differences these differences in drug literature evaluation
    • B4:   To use family history (minimum of three generations) in assessing predisposition to disease and selection of drug treatment
  • Genetics and Disease
    • G1:   To understand the role of genetic factors in maintaining health and preventing disease
    • G2:   To assess the difference between clinical diagnosis of disease and identification of genetic predisposition to disease (genetic variation is not strictly correlated with disease manifestation)
    • G3:   To appreciate that pharmacogenomic testing may also reveal certain genetic disease predispositions (e.g. the Apo E4 polymorphism)
  • Pharmacogenetics/Pharmacogenomics
    • P3:   Recognize the availability of evidence based guidelines that synthesize information relevant to genomic/pharmacogenomic tests and selection of drug therapy (e.g. Clinical Pharmacogenomics Implementation Consortium)

Physician Assistant

  • Patient Care
    • 1:   Gather family history information and construct a multigenerational pedigree.
    • 2:   Identify patients who would benefit from referral to genetics professionals
    • 3:   Distinguish between genetic screening and genetic testing
    • 4:   Incorporate genetic tests into patient management
    • 5:   Discuss the range of genetic and genomic-based approaches to the treatment of disease.
  • Medical Knowledge For Practice
    • 1:   Describe the cellular and molecular mechanisms underlying human inheritance.
    • 2:   Define the role of genetic variation in health and disease
  • Interpersonal & Communications Skills
    • 1:   When communicating genetic information to patients, consider personal factors that may influence their understanding and response.
    • 2:   Explain the role of genetics professionals in the patient-care plan
    • 3:   Promote informed decision making for patients, and provide nondirective counseling
  • Practiced-based Learning and Improvement
    • 1:   Use information technology to obtain current and credible information about genetics for self, patients, and colleagues
  • PROFESSIONALISM
    • 1:   Examine on a regular basis one's competence in genetics/genomics as pertinent to one’s practice setting

Nurse

  • Professional Responsibilities
    • PR-1:   Recognize one's own attitudes and values
    • PR-5:   Demonstrate the importance of tailoring genetic and genomic information and services
  • Nursing Assessment
    • NA-1:   Demonstrate understanding of relationship of genetics and genomics to health
  • Identification
    • ID-1:   Identify clients who may benefit from genetic and genomic information and services
    • ID-2:   Identify credible, accurate, appropriate, and current genetic and genomic information
  • Provision of education, care and support
    • PECS-2:   Provide clients with genetic and genomic information and resources for informed decision making
    • PECS-3a:   Use health promotion/disease prevention practices that consider genetic and genomic influences
    • PECS-3b:   Use health promotion/disease prevention practices incorporating knowledge of genetic and/or genomic risk factors
    • PECS-4:   Use genetic- and genomic-based interventions and information to improve clients' outcomes
    • PECS-5:   Collaborate with health care providers to provide genetic and genomic health care in health promotion/disease prevention
    • PECS-8:   Evaluate impact and effectiveness of technology, information, interventions, and treatments

Genetic Counselor

  • Genetics Expertise and Analysis
    • 1:   Demonstrate and utilize a depth and breadth of understanding and knowledge of genetics and genomics core concepts and principles.
    • 4:   Identify, assess, facilitate, and integrate genetic testing options in genetic counseling practice.
    • 7:   Critically assess genetic/genomic, medical and social science literature and information.