Human Genome Program of the Department of Energy

Completed in 2003, the Human Genome Project (HGP) was a 13-year project coordinated by the U.S. Department of Energy (DOE) and the National Institutes of Health. During the early years of the HGP, the Wellcome Trust (U.K.) became a major partner; additional contributions came from Japan, France, Germany, China, and others. Project goals were to

  • identify all the approximately 20,500 genes in human DNA,
  • determine the sequences of the 3 billion chemical base pairs that make up human DNA,
  • store this information in databases,
  • improve tools for data analysis,
  • transfer related technologies to the private sector, and
  • address the ethical, legal, and social issues (ELSI) that may arise from the project.

Though the HGP is finished, analyses of the data will continue for many years.


Type Website
CME Available No
Topic
Cost Free
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Genomic Competencies

Experts from the disciplines listed below have tagged this resource as fulfulling genomic competencies.

Pharmacist

  • Basic Genetic Concepts
    • B1:   To demonstrate an understanding of the basic genetic/genomic concepts and nomenclature
    • B2:   To recognize and appreciate the role of behavioral, social, and environmental factors (lifestyle, socioeconomic factors, pollutants, etc.) to modify or influence genetics in the manifestation of disease
    • B4:   To use family history (minimum of three generations) in assessing predisposition to disease and selection of drug treatment
  • Genetics and Disease
    • G1:   To understand the role of genetic factors in maintaining health and preventing disease
    • G2:   To assess the difference between clinical diagnosis of disease and identification of genetic predisposition to disease (genetic variation is not strictly correlated with disease manifestation)
    • G3:   To appreciate that pharmacogenomic testing may also reveal certain genetic disease predispositions (e.g. the Apo E4 polymorphism)

Physician Assistant

  • Medical Knowledge For Practice
    • 1:   Describe the cellular and molecular mechanisms underlying human inheritance.
    • 2:   Define the role of genetic variation in health and disease

Nurse

  • Professional Responsibilities
    • PR-2:   Advocate for clients' access
      • PR2-K1:   Resources for healthcare professionals and lay public
        • PR2-2:   Demonstrate knowledge about accessing local/regional genetic and/or genomic resources.
      • PR2-K2:   Resources for genetic and/or genomic referrals within one's community
        • PR2-2:   Demonstrate knowledge about accessing local/regional genetic and/or genomic resources.
    • PR-3:   Examine competency of practice
      • PR3-K1:   Scope of nursing practice in relation to genetics/genomics
        • PR3-1:   Identify relevance of genetics/genomics to practice of your discipline.
        • PR3-4:   Take action to meet identified knowledge and skills deficits related to genetics and genomics.
      • PR3-K2:   Role of specialist genetic/genomic services
        • PR3-1:   Identify relevance of genetics/genomics to practice of your discipline.
        • PR3-4:   Take action to meet identified knowledge and skills deficits related to genetics and genomics.
      • PR3-K3:   Interprofessional resources
        • PR3-1:   Identify relevance of genetics/genomics to practice of your discipline.
        • PR3-4:   Take action to meet identified knowledge and skills deficits related to genetics and genomics.
    • PR-4:   Incorporate genetic and genomic technologies and information into practice.
      • PR4-K1:   Technology and information systems
        • PR4-3:   Identify the credibility, reliability and limitations of genetic and genomic information.
        • PR4-4:   Identify ethical, legal, and social issues associated with genetic/genomic information.
    • PR-5:   Demonstrate the importance of tailoring genetic and genomic information and services
      • PR5-K1:   Cultural, social, ethnic and religious perspectives
        • PR5-1:   Incorporate client's cultural, social, ethnic and religious perspective and literacy level when delivering genetic and genomic care.
        • PR5-2:   Integrate knowledge from psychology, history, politics, sociology and culture when delivering genetic and genomic care.
      • PR5-K2:   Economic and health disparities
        • PR5-1:   Incorporate client's cultural, social, ethnic and religious perspective and literacy level when delivering genetic and genomic care.
        • PR5-2:   Integrate knowledge from psychology, history, politics, sociology and culture when delivering genetic and genomic care.
    • PR-6:   Advocate for the rights of all clients
      • PR6-K1:   Potential benefits, risks and limitations
        • PR6-3:   Demonstrate awareness of the potential impact of genetic/genomic information on the individual and other family members.
        • PR6-4:   Respond appropriately to inquiries about genetic and genomic health care concerns.
      • PR6-K2:   Ethical, legal and social issues
        • PR6-3:   Demonstrate awareness of the potential impact of genetic/genomic information on the individual and other family members.
        • PR6-4:   Respond appropriately to inquiries about genetic and genomic health care concerns.
      • PR6-K3:   Impact of genetic and genomic information
        • PR6-3:   Demonstrate awareness of the potential impact of genetic/genomic information on the individual and other family members.
        • PR6-4:   Respond appropriately to inquiries about genetic and genomic health care concerns.
      • PR6-K4:   Components of informed decision-making
        • PR6-3:   Demonstrate awareness of the potential impact of genetic/genomic information on the individual and other family members.
        • PR6-4:   Respond appropriately to inquiries about genetic and genomic health care concerns.
  • Nursing Assessment
    • NA-1:   Demonstrate understanding of relationship of genetics and genomics to health
      • NA1-K1:   Relationship of genetics and genomics to health
        • NA1-3:   Identify clients who might benefit from referral to genetic specialists and/or information resources.
        • NA1-6:   Describe genetic/genomic factors that contribute to variability of response to pharmacologic agents.
        • NA1-8:   Identify resources available to assist clients seeking genetic and genomic information or services including the types of services available.
      • NA1-K2:   Relationship of genetics and genomics to normal physiology and pathophysiology
        • NA1-3:   Identify clients who might benefit from referral to genetic specialists and/or information resources.
        • NA1-6:   Describe genetic/genomic factors that contribute to variability of response to pharmacologic agents.
        • NA1-8:   Identify resources available to assist clients seeking genetic and genomic information or services including the types of services available.
      • NA1-K3:   Basic principles of pharmacogenetics and pharmacogenomics
        • NA1-3:   Identify clients who might benefit from referral to genetic specialists and/or information resources.
        • NA1-6:   Describe genetic/genomic factors that contribute to variability of response to pharmacologic agents.
        • NA1-8:   Identify resources available to assist clients seeking genetic and genomic information or services including the types of services available.
      • NA1-K4:   Patterns of disease associated with single gene and multifactorial inheritance
        • NA1-3:   Identify clients who might benefit from referral to genetic specialists and/or information resources.
        • NA1-6:   Describe genetic/genomic factors that contribute to variability of response to pharmacologic agents.
        • NA1-8:   Identify resources available to assist clients seeking genetic and genomic information or services including the types of services available.
    • NA-7:   Assess client's knowledge, perceptions, and responses
      • NA7-K1:   Cultural, social, ethnic and religious perspectives
        • NA7-1:   Demonstrate the ability to assess clients cultural, religious and ethnic perspectives with regards to genetics and genomics.
        • NA7-11:   Demonstrate assessment of the clients' understanding of genetic and genomic information.
        • NA7-12:   Demonstrate assessment of social and psychological responses to genetic/genomic information.
        • NA7-7:   Identify situations where clients' own beliefs and/or values influence genetic and genomic care choices.
      • NA7-K2:   Social and psychological implications of accessing genetic services and information
        • NA7-1:   Demonstrate the ability to assess clients cultural, religious and ethnic perspectives with regards to genetics and genomics.
        • NA7-11:   Demonstrate assessment of the clients' understanding of genetic and genomic information.
        • NA7-12:   Demonstrate assessment of social and psychological responses to genetic/genomic information.
        • NA7-7:   Identify situations where clients' own beliefs and/or values influence genetic and genomic care choices.
      • NA7-K3:   Ethical and legal issues
        • NA7-1:   Demonstrate the ability to assess clients cultural, religious and ethnic perspectives with regards to genetics and genomics.
        • NA7-11:   Demonstrate assessment of the clients' understanding of genetic and genomic information.
        • NA7-12:   Demonstrate assessment of social and psychological responses to genetic/genomic information.
        • NA7-7:   Identify situations where clients' own beliefs and/or values influence genetic and genomic care choices.
      • NA7-K4:   Principles of autonomous decisionmaking in genetic counseling
        • NA7-1:   Demonstrate the ability to assess clients cultural, religious and ethnic perspectives with regards to genetics and genomics.
        • NA7-11:   Demonstrate assessment of the clients' understanding of genetic and genomic information.
        • NA7-12:   Demonstrate assessment of social and psychological responses to genetic/genomic information.
        • NA7-7:   Identify situations where clients' own beliefs and/or values influence genetic and genomic care choices.
      • NA7-K5:   Principles of client genetic/genomic education and counseling
        • NA7-1:   Demonstrate the ability to assess clients cultural, religious and ethnic perspectives with regards to genetics and genomics.
        • NA7-11:   Demonstrate assessment of the clients' understanding of genetic and genomic information.
        • NA7-12:   Demonstrate assessment of social and psychological responses to genetic/genomic information.
        • NA7-7:   Identify situations where clients' own beliefs and/or values influence genetic and genomic care choices.
    • NA-8:   Develop a plan of care that incorporates genetic and genomic assessment information.
      • NA8-K1:   Interprofessional plan of care
        • NA8-2:   Integrate best evidence, clinical judgment, client preferences, and family implications in planning genetic and genomic focused individualized care.
  • Identification
    • ID-1:   Identify clients who may benefit from genetic and genomic information and services
      • ID1-K1:   Components of family history needed to identify disease susceptibility or genetic/genomic condition
        • ID1-2:   Identify clients who may benefit from further evaluation of the identified disease susceptibility or genetic/genomic condition.
        • ID1-3:   Demonstrate assessment of client concerns or understanding about information received from specialty genetic services (i.e., on-line genetic testing results).
        • ID1-4:   Uses genetic and genomic indicators as rationale for clients who may benefit from further evaluation or other risk management interventions.
      • ID1-K2:   Inheritance patterns
        • ID1-2:   Identify clients who may benefit from further evaluation of the identified disease susceptibility or genetic/genomic condition.
        • ID1-3:   Demonstrate assessment of client concerns or understanding about information received from specialty genetic services (i.e., on-line genetic testing results).
        • ID1-4:   Uses genetic and genomic indicators as rationale for clients who may benefit from further evaluation or other risk management interventions.
      • ID1-K3:   Indicators of disease susceptibility or a genetic condition
        • ID1-2:   Identify clients who may benefit from further evaluation of the identified disease susceptibility or genetic/genomic condition.
        • ID1-3:   Demonstrate assessment of client concerns or understanding about information received from specialty genetic services (i.e., on-line genetic testing results).
        • ID1-4:   Uses genetic and genomic indicators as rationale for clients who may benefit from further evaluation or other risk management interventions.
      • ID1-K4:   Common health conditions with a genetic/genomic component
        • ID1-2:   Identify clients who may benefit from further evaluation of the identified disease susceptibility or genetic/genomic condition.
        • ID1-3:   Demonstrate assessment of client concerns or understanding about information received from specialty genetic services (i.e., on-line genetic testing results).
        • ID1-4:   Uses genetic and genomic indicators as rationale for clients who may benefit from further evaluation or other risk management interventions.
      • ID1-K5:   Indicators of need for targeted treatment selection
        • ID1-2:   Identify clients who may benefit from further evaluation of the identified disease susceptibility or genetic/genomic condition.
        • ID1-4:   Uses genetic and genomic indicators as rationale for clients who may benefit from further evaluation or other risk management interventions.
    • ID-2:   Identify credible, accurate, appropriate, and current genetic and genomic information
      • ID2-K1:   Resources for health care professionals and lay public
        • ID2-1:   Evaluate strengths, limitations, and best use of genetic and/or genomic resource for a client or group of clients.
        • ID2-2:   Discuss the ways in which nurses can meet the educational, psychosocial and resource needs of clients and families affected by a genetic or genomic condition.
        • ID2-3:   Discuss the ways in which nurses can meet the knowledge, psychosocial and resource needs of clients and families affected by genetic/genomic technology.
        • ID2-4:   Identify resources available to assist clients seeking genetic and genomic information or services including the types of services available.
      • ID2-K2:   Resources for referral within one's community
        • ID2-1:   Evaluate strengths, limitations, and best use of genetic and/or genomic resource for a client or group of clients.
        • ID2-2:   Discuss the ways in which nurses can meet the educational, psychosocial and resource needs of clients and families affected by a genetic or genomic condition.
        • ID2-3:   Discuss the ways in which nurses can meet the knowledge, psychosocial and resource needs of clients and families affected by genetic/genomic technology.
        • ID2-4:   Identify resources available to assist clients seeking genetic and genomic information or services including the types of services available.
      • ID2-K3:   Roles of genetic/genomic health care professionals
        • ID2-1:   Evaluate strengths, limitations, and best use of genetic and/or genomic resource for a client or group of clients.
        • ID2-2:   Discuss the ways in which nurses can meet the educational, psychosocial and resource needs of clients and families affected by a genetic or genomic condition.
        • ID2-3:   Discuss the ways in which nurses can meet the knowledge, psychosocial and resource needs of clients and families affected by genetic/genomic technology.
        • ID2-4:   Identify resources available to assist clients seeking genetic and genomic information or services including the types of services available.
      • ID2-K4:   Interprofessional resources
        • ID2-1:   Evaluate strengths, limitations, and best use of genetic and/or genomic resource for a client or group of clients.
        • ID2-2:   Discuss the ways in which nurses can meet the educational, psychosocial and resource needs of clients and families affected by a genetic or genomic condition.
        • ID2-3:   Discuss the ways in which nurses can meet the knowledge, psychosocial and resource needs of clients and families affected by genetic/genomic technology.
        • ID2-4:   Identify resources available to assist clients seeking genetic and genomic information or services including the types of services available.
    • ID-3:   Identify ethical, ethnic/ancestral, cultural, religious, legal, fiscal and societal issues
      • ID3-K1:   Cultural, ethnic, family values, traditions, health beliefs and religious perspectives
        • ID3-1:   Demonstrate the ability to assess cultural, language, family values, traditions, health beliefs and religious perspectives that influence access to and use of genetic/genomic information, technology, and services.
        • ID3-2:   Identify cultural, language, family values, traditions, health beliefs and religious perspectives that impact access and use of genetic/genomic information, technology and services.
        • ID3-3:   Identify psychosocial issues and impact of genetic/genomic information, technology and services on individual and the family.
        • ID3-4:   Use ethical principles when deliberating genetic/genomic issues of decision-making, privacy, confidentiality, informed consent, disclosure, access, and personal impact.
      • ID3-K2:   The components of informed decision-making
        • ID3-1:   Demonstrate the ability to assess cultural, language, family values, traditions, health beliefs and religious perspectives that influence access to and use of genetic/genomic information, technology, and services.
        • ID3-2:   Identify cultural, language, family values, traditions, health beliefs and religious perspectives that impact access and use of genetic/genomic information, technology and services.
        • ID3-3:   Identify psychosocial issues and impact of genetic/genomic information, technology and services on individual and the family.
        • ID3-4:   Use ethical principles when deliberating genetic/genomic issues of decision-making, privacy, confidentiality, informed consent, disclosure, access, and personal impact.
      • ID3-K3:   Sources of genetic information
        • ID3-1:   Demonstrate the ability to assess cultural, language, family values, traditions, health beliefs and religious perspectives that influence access to and use of genetic/genomic information, technology, and services.
        • ID3-2:   Identify cultural, language, family values, traditions, health beliefs and religious perspectives that impact access and use of genetic/genomic information, technology and services.
        • ID3-3:   Identify psychosocial issues and impact of genetic/genomic information, technology and services on individual and the family.
        • ID3-4:   Use ethical principles when deliberating genetic/genomic issues of decision-making, privacy, confidentiality, informed consent, disclosure, access, and personal impact.
      • ID3-K4:   Capabilities and limitations of current genetic/genomic technologies
        • ID3-1:   Demonstrate the ability to assess cultural, language, family values, traditions, health beliefs and religious perspectives that influence access to and use of genetic/genomic information, technology, and services.
        • ID3-2:   Identify cultural, language, family values, traditions, health beliefs and religious perspectives that impact access and use of genetic/genomic information, technology and services.
        • ID3-3:   Identify psychosocial issues and impact of genetic/genomic information, technology and services on individual and the family.
        • ID3-4:   Use ethical principles when deliberating genetic/genomic issues of decision-making, privacy, confidentiality, informed consent, disclosure, access, and personal impact.
      • ID3-K5:   Ethical issues related to genetic/genomic information and technology
        • ID3-1:   Demonstrate the ability to assess cultural, language, family values, traditions, health beliefs and religious perspectives that influence access to and use of genetic/genomic information, technology, and services.
        • ID3-2:   Identify cultural, language, family values, traditions, health beliefs and religious perspectives that impact access and use of genetic/genomic information, technology and services.
        • ID3-3:   Identify psychosocial issues and impact of genetic/genomic information, technology and services on individual and the family.
        • ID3-4:   Use ethical principles when deliberating genetic/genomic issues of decision-making, privacy, confidentiality, informed consent, disclosure, access, and personal impact.
      • ID3-K6:   Psychosocial issues and impact of genetic/genomic information
        • ID3-1:   Demonstrate the ability to assess cultural, language, family values, traditions, health beliefs and religious perspectives that influence access to and use of genetic/genomic information, technology, and services.
        • ID3-2:   Identify cultural, language, family values, traditions, health beliefs and religious perspectives that impact access and use of genetic/genomic information, technology and services.
        • ID3-3:   Identify psychosocial issues and impact of genetic/genomic information, technology and services on individual and the family.
        • ID3-4:   Use ethical principles when deliberating genetic/genomic issues of decision-making, privacy, confidentiality, informed consent, disclosure, access, and personal impact.
      • ID3-K7:   Current state, federal, and military policies
        • ID3-1:   Demonstrate the ability to assess cultural, language, family values, traditions, health beliefs and religious perspectives that influence access to and use of genetic/genomic information, technology, and services.
        • ID3-2:   Identify cultural, language, family values, traditions, health beliefs and religious perspectives that impact access and use of genetic/genomic information, technology and services.
        • ID3-3:   Identify psychosocial issues and impact of genetic/genomic information, technology and services on individual and the family.
        • ID3-4:   Use ethical principles when deliberating genetic/genomic issues of decision-making, privacy, confidentiality, informed consent, disclosure, access, and personal impact.
    • ID-4:   Define issues that undermine the rights of all clients for autonomous, informed decision-making
      • ID4-K1:   Current state, federal, and military policies
        • ID4-3:   Describe legal and social issues related to access and use of genetic information and technology.
      • ID4-K2:   The components of informed decision-making
        • ID4-3:   Describe legal and social issues related to access and use of genetic information and technology.
      • ID4-K3:   Past and potential for misuse of genetic/genomic information and technology
        • ID4-3:   Describe legal and social issues related to access and use of genetic information and technology.
      • ID4-K4:   Guidelines or policies regarding access
        • ID4-3:   Describe legal and social issues related to access and use of genetic information and technology.
  • Provision of education, care and support
    • PECS-1:   Provide clients with interpretation of genetic and genomic information
      • PECS1-K1:   Components of family history
        • PECS1-3:   Discuss the role of genetic, genomic, environmental and psychosocial factors in the manifestation of disease.
        • PECS1-5:   Reinforce/clarify information provided by genetic professional to client (i.e., genetic test interpretation; informed consent).
      • PECS1-K2:   Inheritance Patterns
        • PECS1-3:   Discuss the role of genetic, genomic, environmental and psychosocial factors in the manifestation of disease.
        • PECS1-5:   Reinforce/clarify information provided by genetic professional to client (i.e., genetic test interpretation; informed consent).
      • PECS1-K3:   Role of environmental and psychosocial factors
        • PECS1-3:   Discuss the role of genetic, genomic, environmental and psychosocial factors in the manifestation of disease.
        • PECS1-5:   Reinforce/clarify information provided by genetic professional to client (i.e., genetic test interpretation; informed consent).
      • PECS1-K4:   Informed consent procedures and essential elements
        • PECS1-3:   Discuss the role of genetic, genomic, environmental and psychosocial factors in the manifestation of disease.
        • PECS1-5:   Reinforce/clarify information provided by genetic professional to client (i.e., genetic test interpretation; informed consent).
    • PECS-2:   Provide clients with genetic and genomic information and resources for informed decision making
      • PECS2-K1:   Resources for healthcare professionals and lay public
        • PECS2-2:   Help clients interpret and understand genetic and genomic information.
      • PECS2-K2:   Referral resources for genetic and genomic services within one's community
        • PECS2-2:   Help clients interpret and understand genetic and genomic information.
      • PECS2-K3:   Roles of genetic/genomic health care professionals
        • PECS2-2:   Help clients interpret and understand genetic and genomic information.
    • PECS-8:   Evaluate impact and effectiveness of technology, information, interventions, and treatments
      • PECS8-K1:   Range of psychosocial responses
        • PECS8-1:   Assess client response to genetic/genomic information.
      • PECS8-K2:   Expected outcomes of various genetic/genomic based interventions
        • PECS8-1:   Assess client response to genetic/genomic information.